CyBio® Well vario
plus d'imagesOverview
96, 384 and 1536 Channel Simultaneous Pipettor
Designed for high throughput applications within the screening environment, the CyBio Well vario easily implements your high-precision needs for automated pipetting and can be adapted to specific applications at any time.
The CyBio® Well vario includes an automated base which accepts different interchangeable simultaneous pipetting heads. The heads can be changed quickly and easily either at the front or the back of the instrument. After head exchanges the calibration maintains. A working volume range of four orders of magnitude allows liquid transfers from 25 nL up to 250 µL on one platform, either with 96 or 384 disposable tips. The CyBio® Well vario adapts into any screening environment and it is compatible with all other accessories of the CyBio® Well family.
- Simultaneous pipetting of high density plate formats
- Highest precision through the proven pipetting and tip sealing technology
- Highest flexibility through interchangeable pipetting heads and accessories
- Real high throughput processing thanks to 1536 fold simultaneous pipetting
The CyBio® Well vario is an automated, simultaneous pipetting platform, which accepts a series of different interchangeable pipetting heads, thus combining high flexibility with upgradeability for future tasks. The CyBio® Well vario fulfills your high-precision pipetting requirements with a constant performance over the entire volume range. The CyBio® Well vario adapts into any screening environment and can be equipped with a variety of accessories. Using the air displacement technology, the CyBio® Well vario family guarantees consistently high precision in the range from 100 nL to 250 µL. The use of the disposable polypropylene tips or the reusable glass tips with the CyBio® Well vario head 1536/8 µL enables excellent pipetting performance during the execution of cell-based assays.
- 96-, 384 and 1536-channel simultaneous pipetting system
- Extensive volume range with huge range of different interchangable pipetting heads
- Advanced capillary technology for reliable nanolitre pipetting
The innovative CyBio® Composer Software. supports the flexibility of the system and immediately detects the new head.
- Extremely flexible through enormous volume spectrum
- Highest precision in the whole volume range
- Unique pipetting technology prevents cross contamination
- Easy application set-up using CyBio® Composer software
- Saves reagent costs with accurate low volume pipetting
Brochure Life Science Product Guide
Overview Pipetting Tips for Liquid Handling Instruments
Brochure uHTS MALDI Sample Preparation — Beyond Spotting
Pipettierköpfe
Head 96/25 µl
Parallel pipetting of 96 samples in 96, 384 and 1536 well microplates Volume freely selectable in 0,01 µl steps with a working volume up to 25 µl.
Head 96/60 µl
Parallel pipetting of 96 samples in 96, 384 and 1536 well microplates Volume freely selectable in 0,01 µl steps with a working volume up to 60 µl.
Head 96/250 µl
Parallel pipetting of 96 samples in 96, 384 shallow or deep well microplates Volume freely selectable in 0.01 µl steps with a working volume up to 250 µl.
Head 384/25 µl
Parallel pipetting of 384 samples in 384 and 1536 well microplates Volume freely selectable in 0.01 µl steps with a working volume up to 25 µl.
Head 384/60 µl
Parallel pipetting of 384 samples in 384 and 1536 well microplates Volume freely selectable in 0.01 µl steps with a working volume up to 60 µl.
Head 1536/8 µl
Parallel pipetting of 1536 samples in 1536 well microplates Volume freely selectable in 0.01 µl steps with a working volume up to 8 µl.
Capillary Head
Optimized for pipetting of DMSO solutions into dry microplates Available with fix working volumes of 50, 100, 250, 500 nl with ceramic capillaries parallel pipetting of 96 or 384 samples in 96, 384 an 1536 well microplates due to exchangeable magazines.
Specifications
Head 96/25 µl
Volume range:
0.5-25 µl
Precision [CV in %]* of specified volume range:
0.5 ≤ 10%
2-5 µl ≤ 2%
>5-25µl ≤ 1%
Head 96/60 µl
Volume range:
1–60 µl
Precision [CV in %]* of specified volume range:
3-5 µl ≤ 2%
>5-60 µl ≤ 1%
Head 96/250 µl
Volume range:
5-250 µl
Precision [CV in %]* of specified volume range:
25-100 µl ≤ 2%
25-250 µl ≤ 1%
Head 384/25 µl
Volume range:
0.5-25 µl
Precision [CV in %]* of specified volume range:
2-5 µl ≤ 2%
>5-25 µl ≤ 1%
Head 384/60 µl
Volume range:
1–60 µl
Precision [CV in %]* of specified volume range:
3-5 µl ≤ 2%
>5-60 µl ≤ 1%
Head 1536/8 µl
Volume range:
1–8 µl
Precision [CV in %]* of specified volume range:
1-5 µl ≤ 3%
5-8 µl ≤ 2%
Capillary Head
Volume range:
0.050-1 µl
Precision [CV in %]* of specified volume range:
0.025-1,0 µl ≤ 10%
*The specification of precision and trueness is based on the Analytik Jena internal gravimetric and photometric standard measurement procedure, which is published as Annex B7 in the ISO IWA 15 document ” Specification and method for the determination of volumetric performance of automated liquid handling systems“ (www.IWA15.org). The Application Note „Photometric and Gravimetric Liquid Handling Check Procedure to determine the Random Error (Precision) and the Systematic Error (Accuracy) of Automated Liquid Handling Systems (ALHS)“ describes this measuremet procedure in detail.
Every modification of this method may influence the results.
Technical Data
CyBio® Well vario | |
---|---|
Weight | 39,5 kg with 3,4 and 5 place linear transporting unit 49 kg with 10-place circular transporting unit |
Pipetting Channels | 96, 384, 1536 |
Pipetting Tips | Disposable tips/capillaries |
Plate Formats | 96, 384, 1536 |
Plate Capacity | 3 with 3-place linear transporting unit 4 with 4-place linear transporting unit 5 with 5-place linear transporting unit 10 with 10-place circular transporting unit |
Footprint (W x D in mm) | 960 x 370 mm with 3-place linear transporting unit 1300 x 370 mm with 4-place linear transporting unit 1650 x 370 mm with 5-place linear transporting unit 700 x 895 mm with 10-place circular transporting unit |
Height (mm) | 772.5 mm |
Volume Range | Wet pipetting: 50 nl bis 250 μl Dry pipetting: 200 nl bis 250 μl |
Software
The CyBio® Well vario is controlled by the CyBio® Composer Software.
Applications
A three, four, five or ten - position carriage handles high-precision pipetting needs with high flexibility and ample deck space to run the application successfully. The high flexibility of the CyBio® Composer Software supports any application.
- Reformatting
- Replication
- Plate coating
- Biochemical assays
- ADME and cytotoxicity assays
- Compound management Molecular Biology assays (RNA silencing)
- Cell handling
- uHTS MALDI Sample Preparation — Beyond Spotting
Accessories
Plate Transfer Unit
This additional module can be mounted to the CyBio® Well or CyBio® Well vario and allows the automatic relocation of a microplate to any carriage position.
Microplate adapter
Micro plate adapter allow you to use any type of micro plates of various manufacturers on our devices incl. adapter for specific application requirements.
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Automated Reservoir Filling
The reagent reservoirs are designed for the storage and automatically refilling of liquids, such as buffers, DMSO…
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Barcode Handling
For creation of barcodes, labeling of microplates as well as reading of barcodes within the process we offer tailor-made solutions.
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Tip Wash Station
With the aid of these wash modules, tips in the 96 and 384 format can be washed automatically with pump-supported (active) inflow and drain, which helps you to reduce disposable costs.
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Plate Handling and Storage
Efficient microplate storage with stackers enables fully automated processing of large batches of plates and increases your walk-away time.
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Tip Changer
For high throughput applications, where tip changing is necessary, the TipChanger can store up to 100 tip racks.
Videos
Full Automation CyBio® Well vario
Variable multichannel pipettor.
CyBio® Well vario 1536 Head
The pipetting head uses CyBio® unique and well-proven tip sealing system. The 1536 air displacement pistons allow the simultaneous transfer and filling of all wells of a 1536-well plate in one single step.