multi N/C 2300 Series

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Description

The specialist: A combustion device specializing in the analysis of particle-rich samples and samples that are only present in small volumes.

TOC/TNb analysis for particle-rich samples and special applications

Thanks to the use of direct injection technology, the compact and robust devices of the multi N/C 2300 series are ideal for particle-rich samples. Their modular design makes them customizable for solids as well as for the simultaneous measurement of nitrogen. The septum-free direct injection prevents sample carryover when handling particle-rich liquid samples. Injections from the microliter syringe make it possible to dose extremely small sample volumes, for example for scientific applications. When determining total protein content via total nitrogen analysis in vaccines, these devices offer impressively short measurement times, no carryover and a broad working range.

  • Exceptional particle handling without any blockage or carryover along the sample path
  • Analysis of undiluted samples makes laborious pre-dilution steps redundant
  • New intuitive software with live result display and 21 CFR Part 11 compliant pharma module
  • Reduced workload for staff thanks to the unique VITA flow management system that
  • Ensures long-term stable calibrations
  • Automatic acidification, purging and sample homogenization
  • Five-year warranty on the wide-range focus radiation NDIR detector and the furnace technology

Sophisticated technologies for particle-rich samples and small sample quantities

Difficult matrices and demanding applications need a robust device. The septum-free direct injection from the microliter syringe of the multi N/C 2300 series uses efficient rinsing technology to effectively prevent blockages of the dosing path and any sample carryover even for particle-rich or emulsion-like samples.

The wide-range focus radiation NDIR detector forms the basis of this measuring technology. A broad measurement range of 0 to 30,000 mg/L TOC means that samples can be measured directly without any need for sample dilution. The Easy Cal function enables automatic calibration with long-term stability and reliable standard recovery. The VITA flow management system delivers these benefits by effectively compensating for gas flow fluctuations.

For automatic sample introduction, the autosampler AS 60 offers automatic acidification and purging, as well as magnetic stirring to homogenize liquid samples. A 112 position sample rack for 2 ml HPLC vials is optionally available.

TC and TOC in homogeneous solid samples can be measured with the double furnace module by means of catalytic oxidation at temperatures up to 950 °C in the internal furnace of the multi N/C 2300. In addition, the HT 1300 presents a solids module for catalyst-free combustion of solid samples at up to 1800 °C (with additives) in a ceramic combustion tube. Horizontal sample introduction via ceramic boats enables the direct analysis of solid samples weighing up to 3 g without needing to wrap them into foil. This solids module is part of the multi N/C 2300 duo system including automation, or can be retrofitted with manual or automatic sample introduction at any time.

To measure nitrogen, a reliable electrochemical detector (ChD) can optionally be integrated in the device. Alternatively, a chemiluminescence detector (CLD) can be added as a separate detector module - either during initial analyzer configuration or later.

Variantes d’appareil

multi N/C 2300

This TOC/TNb analyzer is suitable for samples with a high particle or oil content in the field of environmental analysis. By dosing directly from the microliter syringe, the device offers extremely economical sample handling, making an excellent choice for research applications.

Solids analysis (optional, manual)

  • Non-catalytic high-temperature combustion with HT 1300
  • Acid digestion module for TIC analysis in solids
  • Double furnace solids module for catalytic high-temperature combustion

Nitrogen analysis (optional)

  • Simultaneous measurement of TOC and TNb
  • ChD detector (integrated in the device)
  • CLD-300 detector module (can be retrofitted)

Applications:

  • Wastewater analysis in sewage treatment plants
  • Analysis of industrial wastewater and eluates
  • Analysis of small sample quantities, for example analysis of soil extracts, percolating water and ice cores for research purposes


multi N/C 2300 duo

The TOC/TNb analyzer with integrated automated solids analysis is designed for water samples with a high particulate and oil content as well as for less homogeneous solid samples.

Solids analysis:

  • Automated non-catalytic high-temperature combustion at up to 1800 °C (with additives) in a ceramic combustion tube
  • Optional: Acid digestion module for TIC analysis in solids

Nitrogen analysis (optional)

  • Simultaneous measurement of TOC and TNb
  • ChD detector ( integrated in the device)
  • CLD-300 detector module (can be retrofitted)

Applications

  • Wastewater analysis in sewage treatment plants
  • Analysis of industrial wastewater and eluates
  • Analysis of small sample quantities, for example analysis of soil extracts, percolating water and ice cores for research purposes
  • Analysis of soils, contaminated sites, sediment, waste, construction debris

 
multi N/C 2300 N

Nitrogen analyzer for total protein determination using high-temperature catalytic combustion and CLD detection. This device is particularly well suited for small sample volumes and high throughput applications thanks to its high level of automation and short measuring times. The analyzer is compliant with the method of total protein determination listed in the pharmacopoeia.

Automation

  • Analysis of large sample sequences with the integrated AS 60 autosampler and the 112 position rack
  • Use of 2 ml HPLC vials translates to huge savings in terms of sample volume

Nitrogen analysis

  • Contains CLD-300 detector module by default

Applications

  • Quality control of vaccines
  • TN determination in aqueous protein solutions in the pharmaceutical industry

Données techniques

 

multi N/C 2300 - Direct injection TOC analyzer
450-500.100-2

Detector

Focus Radiation NDIR

Optional Parameters

TNb (ChD/CLD)

Injection Volume

50 - 500 µL

Parameters

TC, TIC, TOC, DOC, NPOC, NPOCplus

Digestion Mode

Catalytic high temperature combustion up to 950°C

Gas supply

Oxygen 4.5 or synthetic air (CO2 <1 ppm, hydrocarbons <0.5 ppm)

Limit of Detection

50 µg/L

Measurement Range

0 - 30000 mg/L

Sample Supply

Direct injection

Measuring Time

3 - 5 min

Precision

1 - 2 %

Dimension (width x depth x height)

513 mm x 464 mm x 550 mm

 

multi N/C 2300 duo - Fully automated TOC analyzer for liquids and solids
450-500.104-2

Detector

Focus Radiation NDIR

Optional Parameters

TNb (ChD/CLD)

Injection Volume

50 - 500 µL

Parameters

TC, TIC, TOC, DOC, NPOC, NPOCplus

Digestion Mode

Catalytic high temperature combustion up to 950°C & Catalyst-free oxidation up to 1300°C

Gas supply

Oxygen 4.5 or synthetic air (CO2 <1 ppm, hydrocarbons <0.5 ppm)
Oxygen 2.5

Limit of Detection

50 µg/L

Measurement Range

0 - 30000 mg/L

Sample Supply

Direct injection

Measuring Time

3 - 5 min

Precision

1 - 2 %

Dimension (width x depth x height)

1865 mm x 650 mm x 970 mm

 

multi N/C 2300 N - TN analyzer for aqueous protein solutions
450-500.103-2

Detector

Chemiluminescence Detector (CLD)

Optional Parameters

 

Injection Volume

50 - 500 µL

Parameters

TN

Digestion Mode

High temperature combustion up to 950°C

Gas supply

Oxygen 4.5 or synthetic air (CO2 <1 ppm, hydrocarbons <0.5 ppm)

Limit of Detection

5 µg/L

Measurement Range

0 - 200 mg/L

Sample Supply

Direct injection

Measuring Time

3 - 5 min

Precision

1 - 2 %

Dimension (width x depth x height)

813 mm x 500 mm x 970 mm

Logiciel

multiWin pro - Operation and data evaluation software for TOC/TNb analyzers

The new intuitive software multiWin pro is your user cockpit, with all vital information presented on a single screen. It monitors all key system parameters, clearly presents the measurement results and enables comfortable and targeted operation thanks to its automated, user-friendly workflows. It also offers optional data integrity functions in accordance with FDA 21 CRF Part 11.

The software includes the following features:

  • Sequence table: Live results update, option to measure a single sample using different methods
  • Calibration: Automatic calibration during the measurement sequence with the calibration evaluation applied to subsequent sample measurements
  • Easy Cal: Multi-point calibration from a single standard, including blank correction
  • Reporting: Data evaluation and generation of result reports during an ongoing sequence; user-specific choice of units
  • Conversion functions: Conversion of TOC results into CSB and BSB5 equivalents, TIC values into CO2 levels, and total nitrogen results into total protein contents
  • Self-diagnostics: Automatic and permanent leakage monitoring as well as monitoring of input pressure and internal device pressure, tracking of maintenance intervals, furnace and Peltier temperature, as well as detector status (self-check system)
  • Data export: Automatic or manual in LIMS, CSV and PDF formats

 

FDA 21 CFR Part 11 Compliance module for multiWin pro

Software module for FDA 21 CFR Part 11 conformity and data integrity

  • 21 CFR Part 11-compliant user management with user roles and assignment of individual permissions
  • Electronic signatures (3-stage) for release of calibration reports, methods and analysis results
  • Active Directory connection
  • Audit trail with comprehensive filtering function to track changes made by users
  • Configurable password rules
  • IQ, OQ and PQ documentation optimized for pharmaceutical applications
  • Software validation documentation and service provision by our support team, including certificate

Accessoires

AS 60 Autosampler for direct injection TOC/TNb analyzers: Autosampler for all direct injection TOC/TNb analyzers with 60 or 112 sample positions. Automatic sample acidification and homogenization as well as effective syringe rinse included.

HT 1300 for multi N/C 2300 - solids combustion module for TC/TOC analysis: Accessory module for determination of TC and TOC in solids by robust catalyst-free oxidation in a ceramic combustion tube at up to 1,300 °C

TIC solids module manual: Accessory module for semi-automated, direct determination of total inorganic carbon (TIC) in solid samples by acid decomposition.

Double Furnace solids module for multi N/C 2300: Horizontal sample introduction by quartz boats for determination of TC and TOC in solids by catalytic combustion at up to 950 °C

Téléchargements

Videos

multi N/C x300 Series — Sample Handling and Injection Techniques

The TOC/TNb analyzers of the multi N/C series utilize unique injection techniques to transfer the sample into the combustion chamber. See how the innovative flow injection system with intelligent rinsing of the multi N/C 3300 works or discover the valve-free, direct injection system of the multi N/C 2300S which reduces the risk of sample carry-over significantly. All injection techniques ensure reliable and fast TOC/TNb analyses for almost every sample matrix.

multi N/C x300 Series - TOC analysis with the Focus Radiation NDIR Detector

Discover the cutting-edge technology behind Analytik Jena’s multi N/C x300 series for total organic carbon (TOC) and total bound nitrogen (TNb) analysis. One of the highlights is the cleverly designed focus radiation NDIR detector. Unlike conventional detectors, it offers outstanding sensitivity and long-term signal stability. No moving parts, zero maintenance, and a 5-year warranty make it a game-changer for your lab.The advantages of the detector at a glance:• Corrosion-proof• Long-term signal stability• Precise measurement results• No moving parts• No maintenance• No operating costs• 5-year long-term warrantyThe new multi N/C x300 series of TOC/TNb analyzers uses unique technologies and intuitive software to simplify your daily laboratory routine while providing results suitable for any interlaboratory study.

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